Description

2-Nitro-4-Trifluoromethyl-Biphenyl is a specialized biphenyl derivative featuring both nitro and trifluoromethyl functional groups, making it a valuable fluorinated aromatic intermediate. This compound matters for its role in synthesizing advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group contributes to improved biological activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a core structure in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials for electronic displays.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or optical properties.
• Organic Synthesis Research: A versatile substrate for cross-coupling reactions (e.g., Suzuki, Heck) and nitro-group reduction studies in academic and industrial R&D laboratories.
• Fluorinated Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments with enhanced light-fastness and color properties.

Basic Information

Product Name	2-Nitro-4-Trifluoromethyl-Biphenyl
CAS No.	2613-38-9
Molecular Formula	C₁₃H₈F₃NO₂
Molecular Weight	267.21 g/mol
Synonyms	2-Nitro-4'-(trifluoromethyl)biphenyl; 4'-Trifluoromethyl-2-nitrobiphenyl; 1-Nitro-2-(4-trifluoromethylphenyl)benzene; [1,1'-Biphenyl]-2-nitro-4'-trifluoromethyl; 2-Nitro-4'-trifluoromethyl-1,1'-biphenyl; α-Nitro-α,α,α-trifluoro-p-terphenyl (historical); 2-Nitro-4-trifluoromethyl diphenyl
EINECS	Contact for details

Quality Control

Our 2-Nitro-4-Trifluoromethyl-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.