Description

8-Acetoxyquinoline is a versatile quinoline derivative primarily used as a key synthetic intermediate in the production of more complex organic molecules. Its value lies in the reactivity of the acetoxy group, which allows for efficient functionalization and the construction of pharmacologically active compounds. This high-purity intermediate is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers working on advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those with quinoline-based structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the quinoline moiety imparts specific biological activity.
• Material Science Research: Acts as a precursor for developing functional organic materials, including ligands for metal-organic frameworks (MOFs) and catalysts.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and creating novel chemical entities.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinoline-based dyes and colorants.
• Coordination Chemistry: Functions as a derivatized ligand precursor for complexing with various metal ions in catalytic systems.

Basic Information

Product Name	8-Acetoxyquinoline
CAS No.	2598-29-0
Molecular Formula	C11H9NO2
Molecular Weight	187.20 g/mol
Synonyms	8-Quinolyl acetate; Quinolin-8-yl acetate; 8-Hydroxyquinoline acetate ester; 8-(Acetyloxy)quinoline; 8-Quinolinol acetate; Acetic acid 8-quinolyl ester; 8-Acetoxy-chinolin; 8-Oxo-8H-acenaphthylen-1-yl acetate (obsolete)
EINECS	220-008-5

Quality Control

Our 8-Acetoxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC or GC purity data, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.