Description

(R,R)-Methyl 3-Amino-2-Methylbutyrate Hcl CAS NO 2576-40-1 is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry, which is crucial for creating enantiomerically pure compounds with specific biological activities. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry affects efficacy and environmental profile.
• Peptidomimetics Research: Serves as a constrained, non-proteinogenic amino acid ester analog for constructing novel peptide-like structures in medicinal chemistry.
• Catalyst and Ligand Preparation: A precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in stereoselective synthesis and total synthesis projects.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(R,R)-Methyl 3-Amino-2-Methylbutyrate Hydrochloride
CAS No.	2576-40-1
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	(2R,3R)-Methyl 3-Amino-2-Methylbutanoate Hydrochloride; Methyl (2R,3R)-3-Amino-2-Methylbutyrate HCl; (R,R)-3-Amino-2-Methylbutyric Acid Methyl Ester Hydrochloride; L-threonine derivative; (2R,3R)-3-Amino-2-methylbutyric acid methyl ester hydrochloride; Methyl (2R,3R)-3-amino-2-methylbutanoate hydrochloride
EINECS	Contact for details

Quality Control

Our (R,R)-Methyl 3-Amino-2-Methylbutyrate HCl is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Maximum Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.