Description

n-Me-Dl-Val-Oh Hcl is a protected amino acid derivative, specifically the hydrochloride salt of N-methyl-DL-valine. This compound is a crucial chiral building block and intermediate in advanced organic synthesis, valued for its role in modifying peptide backbones and introducing specific steric and chemical properties. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in peptide mimetics and protease inhibitors.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate N-methylated valine residues, which can enhance metabolic stability and alter conformational properties of peptides.
• Agrochemical Synthesis: Acts as a building block for creating chiral active ingredients in crop protection agents.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and as a precursor in medicinal chemistry programs.
• Bioconjugation: Can be utilized in the synthesis of linkers and modified biomolecules for bioconjugation applications.
• Catalyst & Ligand Development: Functions as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	n-Me-Dl-Val-Oh Hcl
CAS No.	2566-32-7
Molecular Formula	C6H13NO2 • HCl
Molecular Weight	167.63 g/mol (Free base: 131.17 g/mol)
Synonyms	N-Methyl-DL-valine hydrochloride; DL-N-Methylvaline HCl; (±)-N-Methylvaline hydrochloride; 2-(Methylamino)-3-methylbutanoic acid hydrochloride; Valine, N-methyl-, hydrochloride, DL-; 3-Methyl-2-(methylamino)butanoic acid hydrochloride; UNII-2D6T6QPU4H
EINECS	Contact for details

Quality Control

Our n-Me-Dl-Val-Oh Hcl is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We can supply material compliant with various pharmacopeial standards (e.g., USP, EP) for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (typical ratio 50:50)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.