Description

Prop-2-Ynylsulfonylbenzene is a specialized organic building block featuring a sulfonyl group linked to a phenyl ring and a terminal alkyne moiety. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in click chemistry and materials science. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, especially for creating sulfonamide-based bioactive molecules.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition, CuAAC) for bioconjugation and polymer functionalization.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing advanced polymers with specific thermal or mechanical properties.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for labeling biomolecules or creating activity-based probes for proteomics research.

Basic Information

Product Name	Prop-2-Ynylsulfonylbenzene
CAS No.	2525-40-8
Molecular Formula	C9H8O2S
Molecular Weight	180.22 g/mol
Synonyms	Phenyl propargyl sulfone; Propargyl phenyl sulfone; (Phenylsulfonyl)propyne; 1-(Phenylsulfonyl)-2-propyne; Benzenesulfonylpropyne; 2-Propynyl phenyl sulfone; 3-(Phenylsulfonyl)-1-propyne
EINECS	219-775-7

Quality Control

Our Prop-2-Ynylsulfonylbenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.