Description

7-Fluoro-n-Hydroxy-n-2-Acetylaminofluorene is a specialized fluorinated derivative of 2-acetylaminofluorene, a compound of significant interest in biochemical and pharmacological research. Its core value lies in its utility as a key synthetic intermediate or reference standard for studying metabolic pathways, DNA adduct formation, and the biological effects of polycyclic aromatic hydrocarbon derivatives. This compound is primarily needed by research institutions, pharmaceutical R&D laboratories, and chemical manufacturers focused on developing novel therapeutic agents or advanced diagnostic tools.

Application

• Biochemical Research Intermediate: Serves as a crucial building block in the synthesis of more complex fluorinated molecules for biological activity studies.
• Pharmacological Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and validation in drug metabolism and pharmacokinetics (DMPK) research.
• Metabolic Pathway Studies: Employed in investigations of enzymatic activation and detoxification pathways related to polycyclic aromatic compounds.
• Oncology Research: Acts as a tool compound in cancer research to study the mechanisms of carcinogenesis and the role of specific chemical modifications on biological activity.
• Organic Synthesis: Utilized as a fluorinated precursor in advanced organic synthesis for introducing the fluoro-acetylaminofluorene moiety into target molecules.
• Toxicology and Safety Assessment: Applied in toxicological studies to understand the structure-activity relationships (SAR) and potential health impacts of fluoro-substituted aromatics.

Basic Information

Item	Detail
Product Name	7-Fluoro-n-Hydroxy-n-2-Acetylaminofluorene
CAS No.	2508-18-1
Molecular Formula	C₁₅H₁₂FNO₂
Molecular Weight	257.26 g/mol
Synonyms	7-Fluoro-2-acetylaminofluoren-9-ol; 7-Fluoro-N-hydroxy-2-acetylaminofluorene; 7-Fluoro-9-hydroxy-2-acetamidofluorene; 7-F-2-AAF-OH; 7-Fluoro-N-acetoxy-2-acetylaminofluorene; 7-Fluoro-2-AAF-N-OH; 2-Acetamido-7-fluoro-9H-fluoren-9-ol; N-Hydroxy-7-fluoro-2-acetylaminofluorene
EINECS	Contact for details

Quality Control

Our 7-Fluoro-n-Hydroxy-n-2-Acetylaminofluorene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.