Description

Isochlorogenic Acid A CAS NO 2450-53-5 is a significant caffeoylquinic acid isomer, a key bioactive polyphenol found in various medicinal plants. This compound is valued for its potent antioxidant and anti-inflammatory properties, making it a critical standard and active ingredient for research and product development. It is primarily sought by manufacturers in the nutraceutical, pharmaceutical, and cosmetic industries for applications ranging from analytical standards to functional formulations.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and analytical method development in herbal medicine.
• Nutraceutical & Dietary Supplements: Incorporated into formulations for its antioxidant benefits, supporting products aimed at oxidative stress management.
• Cosmetic & Skincare Actives: Serves as a key bioactive ingredient in anti-aging, soothing, and protective skincare serums and creams.
• Biomedical Research: Utilized in in vitro and in vivo studies to investigate mechanisms related to inflammation, metabolic syndrome, and neuroprotection.
• Functional Food & Beverages: Potential additive for enhancing the health profile of beverages and fortified food products.
• Natural Product Isolation & Standardization: Essential for standardizing extracts of Lonicera japonica (honeysuckle), Echinacea, and other botanicals rich in chlorogenic acids.

Basic Information

Product Name	Isochlorogenic Acid A
CAS No.	2450-53-5
Molecular Formula	C25H24O12
Molecular Weight	516.45 g/mol
Synonyms	3,5-Di-O-caffeoylquinic acid; 3,5-Dicaffeoylquinic acid; Isochlorogenic acid; Isochlorogenic acid A; 3-Caffeoylquinic acid 5-caffeoyl ester; 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid 3,5-bis(3-(3,4-dihydroxyphenyl)-2-propenoate); Lonicerin; Cynarine D; Contact for details on additional trade names.
EINECS	219-498-9

Quality Control

Our Isochlorogenic Acid A is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, UV), to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We can supply grades suitable for use as analytical standards, including in-house reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep container tightly sealed in a dry environment to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.