Description

2,2',4,4'-Tetrachlorobiphenyl is a specific congener of polychlorinated biphenyls (PCBs), a well-studied class of synthetic organic chemicals. This compound is of significant importance as a high-purity reference standard and analytical standard for environmental monitoring, toxicological research, and regulatory compliance testing. It is primarily required by analytical laboratories, research institutions, and environmental agencies involved in the identification and quantification of PCB contaminants in various matrices.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of GC-MS, GC-ECD, and HPLC systems in environmental analysis.
• Environmental Monitoring: Essential for quantifying PCB contamination levels in soil, sediment, water, and air samples to assess environmental health and compliance.
• Toxicological & Biomedical Research: Serves as a precise standard in studies investigating the metabolism, pharmacokinetics, and chronic health effects of specific PCB congeners.
• Food & Feed Safety Testing: Employed in the analysis of PCB residues in food products, animal feed, and edible oils to ensure regulatory safety limits are met.
• Method Development & Validation: Critical for developing, optimizing, and validating new analytical methods for PCB detection and quantification.
• Quality Assurance/Quality Control (QA/QC): Used as an internal standard or spike in laboratory proficiency testing and inter-laboratory comparison studies.
• Regulatory Compliance: Supports testing mandated by regulations such as the Stockholm Convention on Persistent Organic Pollutants (POPs), EPA methods, and EU directives.

Basic Information

Product Name	2,2',4,4'-Tetrachlorobiphenyl
CAS No.	2437-79-8
Molecular Formula	C12H6Cl4
Molecular Weight	291.98 g/mol
Synonyms	PCB 47; 2,2',4,4'-Tetrachloro-1,1'-biphenyl; 1,1'-Biphenyl, 2,2',4,4'-tetrachloro-; 2,4,2',4'-Tetrachlorobiphenyl; Tetrachlorobiphenyl (mixed isomers reference); BZ# 47; Congener 47; Aroclor 1242/1254 Component (typical)
EINECS	219-432-8

Quality Control

Our high-purity 2,2',4,4'-Tetrachlorobiphenyl is manufactured and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for critical analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant guidelines for reference material production to support GLP-compliant and ISO/IEC 17025-accredited laboratory operations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term stability, consider storage under an inert atmosphere at lower temperatures (e.g., 2-8°C).

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (GC/MS)	Conforms to reference retention time & mass spectrum
Purity (GC-FID/GC-ECD)	≥ 98.0% (Area %)
Related Substances (HPLC/GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (e.g., hexane, acetone, methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.