Description

D-Threitol is a high-purity, four-carbon sugar alcohol (tetritol) with the CAS number 2418-52-2, serving as a valuable chiral building block and biochemical reagent. Its significance lies in its stereochemical purity, making it an essential intermediate for synthesizing pharmaceuticals, fine chemicals, and advanced materials. This product is critically needed by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for applications ranging from chiral synthesis to cryoprotection.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of antiviral drugs, nucleoside analogs, and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and carbohydrate chemistry research.
• Cryoprotectant: Employed in the preservation of biological samples, cells, and tissues due to its ability to stabilize proteins and membranes at low temperatures.
• Food & Flavor Industry: Functions as a low-calorie sweetener, texturizer, and humectant in specialty food products and flavor formulations.
• Cosmetics & Personal Care: Acts as a moisturizing agent and humectant in skin care formulations, lotions, and creams.
• Chemical Synthesis: Serves as a versatile starting material for producing chiral ligands, polymers, and other complex organic molecules.

Basic Information

Product Name	D-Threitol
CAS No.	2418-52-2
Molecular Formula	C4H10O4
Molecular Weight	122.12 g/mol
Synonyms	(2R,3S)-1,2,3,4-Butanetetrol; D-(-)-Threitol; (2R,3S)-Butane-1,2,3,4-tetrol; Erythritol, D-three-; Threitol, D-; D-Threose, tetrahydro-; Threose Tetrol; NSC 92352
EINECS	219-326-3

Quality Control

Our D-Threitol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. It is typically produced to meet standards suitable for pharmaceutical and research applications, with rigorous testing for identity, potency, and impurities. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and related substances are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-12.5° to -14.5° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (D-enantiomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.