Description

(S)-2-Phenylpropane-1,2-Diol is a high-purity chiral diol building block of significant synthetic utility. Its value lies in its enantiomeric purity, making it a critical intermediate for the production of optically active pharmaceuticals and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop or produce stereospecific active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in anti-inflammatory and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enhancing reaction selectivity and yield.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Polymer Modification: Can be used to introduce chiral centers or hydroxyl functionality into polymer chains for advanced material properties.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-2-Phenylpropane-1,2-Diol
CAS No.	2406-22-6
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(S)-2-Phenyl-1,2-propanediol; (S)-α-Methylbenzyl Glycol; (S)-1-Phenyl-1,2-ethanediol, 2-methyl-; (S)-Styrene Glycol, methyl-; (S)-2-Phenylpropane-1,2-diol; (S)-1-Phenylpropane-1,2-diol; (S)-2-Hydroxy-2-phenylpropyl alcohol; (S)-Atrolactic alcohol
EINECS	219-300-8

Quality Control

Our (S)-2-Phenylpropane-1,2-Diol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.