Description

1-Chloromethyl-4-Methanesulfonyl-Benzene is a versatile and high-value organic synthesis intermediate. This compound matters for its dual functional groups, which make it a critical building block for constructing more complex molecules in advanced chemical synthesis. Pharmaceutical, agrochemical, and specialty chemical manufacturers need this intermediate for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Used in the development of specialized ligands for metal-catalyzed cross-coupling reactions.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for producing specialty polymers with sulfone groups.
• Material Science Research: Intermediate in the creation of organic electronic materials and advanced functional coatings.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	1-Chloromethyl-4-Methanesulfonyl-Benzene
CAS No.	2389-73-3
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	4-(Chloromethyl)phenyl methyl sulfone; p-(Chloromethyl)phenyl methyl sulfone; 1-(Chloromethyl)-4-(methylsulfonyl)benzene; α-Chloro-4-methylsulfonyltoluene; 4-Methylsulfonylbenzyl chloride; (4-Methylsulfonylphenyl)methyl chloride; p-Methylsulfonylbenzyl chloride; Benzene, 1-(chloromethyl)-4-(methylsulfonyl)-
EINECS	219-207-7

Quality Control

Our 1-Chloromethyl-4-Methanesulfonyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.