Description

4-Hydroxyphenethylene Glycol is a versatile phenolic glycol derivative with significant utility as a key synthetic intermediate. Its bifunctional structure, featuring both a phenolic hydroxyl and a glycol moiety, makes it a valuable building block for the creation of more complex molecules. This compound is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its phenolic backbone.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent to introduce hydroxyl functionality into specialty polymers, enhancing adhesion, flexibility, or biocompatibility.
• Liquid Crystal & OLED Materials: Employed in the development of organic electronic materials due to its rigid aromatic core and modifiable side chains.
• Fine Chemical Building Block: Utilized in organic synthesis for constructing complex natural product analogs and other high-value fine chemicals.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Hydroxyphenethylene Glycol
CAS No.	2380-75-8
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	1-(4-Hydroxyphenyl)-1,2-ethanediol; 4-(1,2-Dihydroxyethyl)phenol; p-Hydroxyphenylethylene Glycol; HPG; 4-HPEG; 4-Hydroxymandelic Alcohol; (4-Hydroxyphenyl)glycol; 2-(4-Hydroxyphenyl)ethane-1,2-diol
EINECS	219-174-4

Quality Control

Our 4-Hydroxyphenethylene Glycol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the required specifications for identity, purity, and impurity profiles. We provide Certificates of Analysis (COA) with every shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring GMP-grade intermediates and consistent raw material performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after initial opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.