Description

(2α,5α)-1-Formylaspidofractinine-3β-Carboxylic Acid Methyl Ester is a high-purity, structurally complex indole alkaloid derivative, serving as a critical advanced intermediate in organic synthesis. Its precise stereochemistry makes it an invaluable building block for pharmaceutical research and development, particularly in the synthesis of novel bioactive compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to explore new molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential therapeutic agents targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Alkaloid Synthesis: Serves as a sophisticated intermediate for the total or semi-synthesis of complex natural products and their analogs.
• Biochemical Tool Compound: Potential use in developing probes for studying biological mechanisms and enzyme interactions.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(2α,5α)-1-Formylaspidofractinine-3β-Carboxylic Acid Methyl Ester
CAS No.	2348-67-6
Molecular Formula	C22H26N2O3
Molecular Weight	366.46 g/mol
Synonyms	1-Formylaspidofractinine-3-carboxylic acid methyl ester; Methyl 1-formylaspidofractinine-3-carboxylate; Aspidofractinine-3-carboxylic acid, 1-formyl-, methyl ester; (2α,5α)-1-Formylaspidofractinine-3β-carboxylic Acid Methyl Ester; 3β-Carbomethoxy-1-formylaspidofractinine; Kopsinine derivative
EINECS	Contact for details

Quality Control

Every batch of (2α,5α)-1-Formylaspidofractinine-3β-Carboxylic Acid Methyl Ester is produced and tested under a strict quality management system to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for research-grade materials. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.