Description

1,2-Dichloro-4-Fluoro-5-Nitrobenzene is a high-purity halogenated nitrobenzene derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluoro- and nitro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the halogen and nitro groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing complex azo dyes and other colored compounds.
• Material Science Research: Employed in the development of liquid crystals, organic semiconductors, and polymers due to its electron-withdrawing properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination to create biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and halogen groups make it reactive towards various nucleophiles for introducing diverse functionalities.

Basic Information

Product Name	1,2-Dichloro-4-Fluoro-5-Nitrobenzene
CAS No.	2339-78-8
Molecular Formula	C6H2Cl2FNO2
Molecular Weight	209.99 g/mol
Synonyms	2,3-Dichloro-4-fluoro-1-nitrobenzene; 4-Fluoro-1,2-dichloro-5-nitrobenzene; 5-Nitro-1,2-dichloro-4-fluorobenzene; 1-Nitro-2,3-dichloro-4-fluorobenzene; Benzene, 1,2-dichloro-4-fluoro-5-nitro-; 2339-78-8; DC-FNB
EINECS	Contact for details

Quality Control

Our 1,2-Dichloro-4-Fluoro-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48°C - 52°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.