Description

L-Threitol is a versatile four-carbon sugar alcohol (tetritol) with significant commercial and research utility. Its value lies in its role as a chiral building block and a key intermediate in the synthesis of pharmaceuticals, fine chemicals, and specialty materials. This compound is essential for industries focused on asymmetric synthesis, including pharmaceutical development, agrochemical manufacturing, and advanced material science. Its unique stereochemistry makes it a valuable precursor for nucleoside analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of antiviral drugs, nucleoside analogs, and other active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a building block for asymmetric synthesis in the production of complex organic molecules and specialty chemicals.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway analysis, and carbohydrate chemistry research.
• Cosmetic & Personal Care: Functions as a humectant and moisturizing agent in high-end skincare formulations due to its hygroscopic properties.
• Food Science: Potential use as a low-calorie sweetener or texturizing agent in specialized food products, subject to regulatory approval.
• Material Science: Investigated for use in polymer production and as a component in specialty coatings and resins.

Basic Information

Item	Details
Product Name	L-Threitol
CAS No.	2319-57-5
Molecular Formula	C4H10O4
Molecular Weight	122.12 g/mol
Synonyms	(2S,3S)-1,2,3,4-Butanetetrol; L-(-)-Threitol; (2S,3S)-(-)-Threitol; Threitol; Erythritol stereoisomer; L-Threose tetritol; Threo-1,2,3,4-Butanetetrol
EINECS	219-047-8

Quality Control

Our L-Threitol is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Production adheres to current industry best practices, and each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that meets various customer-specific requirements, including research and pharmaceutical intermediate grades.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider using desiccants or storing under an inert atmosphere to prevent moisture absorption and potential clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-10.0° to -12.0° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.