Description

4-(1-Adamantanyl)-2-Methylaniline Hydrochloride is a high-purity, functionalized aniline derivative featuring the rigid, lipophilic adamantane moiety. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas where the adamantyl group can enhance bioavailability and metabolic stability.
• Agrochemical Research: Serves as a building block for developing new-generation pesticides and herbicides, leveraging the structural robustness of adamantane to improve environmental persistence and efficacy.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, and advanced organic frameworks where its bulky, three-dimensional structure can influence material properties like thermal stability and solubility.
• Organic Synthesis: A versatile reagent for constructing complex molecular architectures in academic and industrial research, enabling C-N bond formation and further functionalization.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in laboratories that synthesize or analyze adamantane-containing compounds.

Basic Information

Item	Details
Product Name	4-(1-Adamantanyl)-2-Methylaniline Hydrochloride
CAS No.	2283-34-3
Molecular Formula	C17H24ClN
Molecular Weight	277.83 g/mol
Synonyms	2-Methyl-4-(tricyclo[3.3.1.1³,⁷]dec-1-yl)aniline hydrochloride; 4-(1-Adamantyl)-2-methylaniline hydrochloride; 2-Methyl-4-adamantylaniline hydrochloride; 4-Adamantyl-2-toluidine hydrochloride; 1-(4-Amino-3-methylphenyl)adamantane hydrochloride; 4-(Adamantan-1-yl)-2-methylbenzenamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-(1-Adamantanyl)-2-Methylaniline Hydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.