Description

Z-Orn(Z)-Oh CAS NO 2274-58-0 is a protected derivative of the amino acid ornithine, featuring a benzyloxycarbonyl (Z) protecting group on both the α-amino and side-chain amino functionalities. This high-purity building block is critical for the controlled synthesis of peptides and complex biomolecules, ensuring precise molecular assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, medicinal chemistry, and proteomics research.

Application

• Peptide Synthesis: Serves as a key protected ornithine residue in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry & Drug Discovery: Used as a scaffold or intermediate in the development of novel therapeutic agents and enzyme inhibitors.
• Bioconjugation: Facilitates the site-specific modification of proteins and other biomolecules due to its orthogonal protecting groups.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the synthesis of peptide-based probes.
• API Intermediate: Acts as a critical intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Academic Research: A fundamental reagent for universities and labs studying amino acid chemistry and peptide structure-activity relationships.

Basic Information

Product Name	Z-Orn(Z)-Oh
CAS No.	2274-58-0
Molecular Formula	C₂₀H₂₂N₂O₆
Molecular Weight	386.40 g/mol
Synonyms	N2,N5-Bis(benzyloxycarbonyl)-L-ornithine; Nα,Nδ-Bis-Cbz-L-ornithine; (S)-2,5-Diamino-2-(benzyloxycarbonylamino)pentanoic acid; H-Orn(Z2)-OH; Z-Orn(Z)-OH; L-Ornithine, N2,N5-bis[(phenylmethoxy)carbonyl]-; Bis-Cbz-L-ornithine; NSC 334379
EINECS	218-888-5

Quality Control

Every batch of Z-Orn(Z)-Oh is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.