Description

3-Chlorosulfonyl-4-Fluoro-Benzoic Acid is a high-value, multi-functional aromatic building block essential for advanced organic synthesis. Its core value lies in the simultaneous presence of a reactive sulfonyl chloride group and a protected carboxylic acid function, enabling precise, sequential derivatization. This compound is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and plant growth regulators that incorporate fluorinated benzoic acid motifs.
• Material Science Precursor: Used in the synthesis of specialized monomers for high-performance polymers and liquid crystals.
• Chemical Research & Development: A versatile starting material for exploring new reaction pathways and creating custom chemical libraries.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, color-fast dyes and functional pigments.

Basic Information

Product Name	3-Chlorosulfonyl-4-Fluoro-Benzoic Acid
CAS No.	2267-40-5
Molecular Formula	C7H4ClFO4S
Molecular Weight	238.62 g/mol
Synonyms	4-Fluoro-3-sulfonylchloride-benzoic Acid; 4-Fluoro-3-chlorosulfonylbenzoic Acid; Benzoic acid, 4-fluoro-3-(chlorosulfonyl)-; 3-(Chlorosulfonyl)-4-fluorobenzoic Acid; 4-Fluoro-m-sulfobenzoic acid chloride; 3-Chlorosulfonyl-p-fluorobenzoic Acid
EINECS	218-875-9

Quality Control

Every batch of 3-Chlorosulfonyl-4-Fluoro-Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.