Description

(1S-Trans)-2,2-Dimethyl-3-(2-Methylprop-1-Enyl)Cyclopropanecarboxylic Acid is a high-purity, optically active cyclopropane derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry and functional group, enabling the construction of complex molecular architectures with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anti-inflammatory, or neurological drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and insecticides where the specific stereochemistry can influence biological activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fragrance and Flavor Chemistry: The cyclopropane ring and side chain can contribute to unique olfactory properties in high-value aroma chemical synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Academic and R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes involving strained ring systems.

Basic Information

Product Name	(1S-Trans)-2,2-Dimethyl-3-(2-Methylprop-1-Enyl)Cyclopropanecarboxylic Acid
CAS No.	2259-14-5
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(1S,3R)-Chrysanthemic Acid; (1S-trans)-Chrysanthemic Acid; (+)-trans-Chrysanthemic Acid; (1S,3R)-2,2-Dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylic Acid; (1R,3S)-2,2-Dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic Acid; trans-(+)-Chrysanthemumic Acid; (1S,3R)-2,2-Dimethyl-3-isobutenylcyclopropanecarboxylic Acid
EINECS	218-850-7

Quality Control

Our (1S-Trans)-2,2-Dimethyl-3-(2-Methylprop-1-Enyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider inert gas atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.