Description

(4-Nitrophenyl)Propiolic Acid is a versatile organic building block characterized by its conjugated alkyne and nitro-substituted aromatic structure. This compound is valued for its dual reactivity, serving as a key intermediate in the synthesis of complex molecules for advanced research and industrial applications. It is primarily sought by professionals in pharmaceutical development, agrochemical research, and materials science for constructing heterocycles, dyes, and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring a nitrophenyl scaffold.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structure can be incorporated into bioactive molecules.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent in the creation of specialty polymers, coatings, and advanced materials with specific optical or electronic properties.
• Dye & Pigment Manufacturing: Serves as a key intermediate for synthesizing azo dyes and other complex colorants due to its reactive alkyne and nitro group.
• Organic Synthesis & Research: Employed in academic and industrial R&D for click chemistry, Sonogashira couplings, and other palladium-catalyzed cross-coupling reactions.
• Liquid Crystal & OLED Materials: Utilized in the development of organic electronic materials, where its rigid, conjugated structure is beneficial.

Basic Information

Item	Detail
Product Name	(4-Nitrophenyl)Propiolic Acid
CAS No.	2216-24-2
Molecular Formula	C9H5NO4
Molecular Weight	191.14 g/mol
Synonyms	4-Nitrophenylpropiolic Acid; p-Nitrophenylpropiolic Acid; 3-(4-Nitrophenyl)prop-2-ynoic Acid; 2-Propynoic acid, 3-(4-nitrophenyl)-; 4-Nitrobenzeneacetylene carboxylic acid; PNPA; (p-Nitrophenyl)acetylene carboxylic acid
EINECS	218-696-5

Quality Control

Our (4-Nitrophenyl)Propiolic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.