Description

Diisopropyl sulfoxide is a high-purity, aprotic polar solvent and versatile chemical intermediate featuring a chiral sulfinyl group. It serves as a critical reagent in asymmetric synthesis—particularly in the preparation of enantiomerically enriched pharmaceuticals and fine chemicals—due to its ability to coordinate with metal catalysts and direct stereoselectivity. Industrial users in pharmaceutical R&D, agrochemical development, and specialty polymer synthesis rely on its consistent performance and low volatility relative to dimethyl sulfoxide (DMSO). Diisopropyl Sulfoxide CAS NO 2211-89-4 is supplied under strict quality controls to ensure batch-to-batch reproducibility and regulatory compliance.

Application

• Chiral auxiliary and ligand in asymmetric catalysis (e.g., asymmetric oxidations, allylations)
• Solvent for transition-metal-catalyzed cross-coupling reactions (Suzuki, Heck, Stille)
• Intermediate in the synthesis of sulfoxide-containing pharmaceuticals (e.g., proton pump inhibitors analogues)
• Stabilizing agent for reactive organometallic species in low-temperature reaction systems
• Co-solvent in electrochemical applications requiring high dielectric constant and thermal stability
• Building block for functionalized sulfoxides used in materials science (e.g., liquid crystals, OLED precursors)

Basic Information

Product Name	Diisopropyl sulfoxide
CAS No.	2211-89-4
Molecular Formula	C6H14OS
Molecular Weight	134.24 g/mol
Synonyms	Diisopropyl sulfoxide; DIPS; 2-(Isopropylsulfinyl)propane; Bis(1-methylethyl) sulfoxide; 1,1′-Sulfinylbis(propane); (i-Pr)2SO; Isopropyl sulfoxide dimer; 2-Propanesulfinic acid, 1,1′-oxybis-
EINECS	218-650-7

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches meet or exceed ACS Reagent Grade specifications for organic solvents, including strict limits on residual metals, water content, and volatile impurities. Testing includes identity confirmation (IR, NMR), assay (HPLC), and trace impurity profiling (GC-MS). The product is manufactured under ISO 9001-certified processes and complies with REACH and applicable FDA guidelines for research-use chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15–25°C) in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity; use desiccant-equipped secondary packaging for long-term storage. Avoid contact with strong acids, strong alkalis, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identity (IR)	Conforms to reference spectrum
Assay (by HPLC)	≥ 99.0%
Water (Karl Fischer)	≤ 0.1%
Residue on evaporation	≤ 0.05%
Heavy metals (as Pb)	≤ 10 ppm
Non-volatile residue	≤ 0.02%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.