Description

n-Isopropylacrylamide (CAS NO 2210-25-5) is a versatile and highly functional acrylamide derivative that serves as a critical building block for advanced polymers. Its primary value lies in its ability to impart unique temperature-responsive properties to materials, making them "smart" and adaptable to environmental changes. This monomer is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over polymer behavior for cutting-edge applications.

Application

• Thermo-responsive Polymers & Hydrogels: Key monomer for synthesizing poly(N-isopropylacrylamide) (PNIPAM), which exhibits a sharp lower critical solution temperature (LCST) near 32°C, enabling applications in drug delivery, tissue engineering, and smart coatings.
• Drug Delivery Systems: Used to create nanocarriers and microgels that can encapsulate and release therapeutic agents in response to specific body temperatures or external thermal triggers.
• Biotechnology & Bioseparation: Employed in the fabrication of "smart" surfaces for cell culture, protein purification, and biosensors that can reversibly change properties with temperature.
• Advanced Material Science: Serves as a co-monomer to introduce thermo-sensitivity into various copolymers for use in actuators, membranes, and optical devices.
• Research & Development: A fundamental reagent in academic and industrial R&D for exploring new stimuli-responsive materials and their mechanisms.

Basic Information

Product Name	n-Isopropylacrylamide
CAS No.	2210-25-5
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	N-Isopropylacrylamide; NIPAM; N-(1-Methylethyl)-2-propenamide; 1-Acrylamido-2-methylpropane; N-Isopropylprop-2-enamide; NIPAAm; IPAAm; Acrylamide, N-isopropyl-
EINECS	218-645-8

Quality Control

Our n-Isopropylacrylamide is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, which is critical for reproducible polymer synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, moisture content, and inhibitor levels. For research and pharmaceutical-grade applications, we can supply material with enhanced purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept tightly sealed after opening to minimize exposure to moisture and light. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	60 - 65 °C
Loss on Drying	≤ 1.0 %
Inhibitor (MEHQ)	50 - 250 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.