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4H-Dibenzo(De,G)Quinolin-9-Ol, 5,6,6A,7-Tetrahydro-1,2,10-Trimethoxy-6 -Methyl-, (S)- CAS NO 2169-44-0
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CAS No.:2169-44-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4H-Dibenzo(De,G)Quinolin-9-Ol, 5,6,6A,7-Tetrahydro-1,2,10-Trimethoxy-6 -Methyl-, (S)- is a high-purity, optically active alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block or intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of complex natural product analogs.
Application
- Pharmaceutical Intermediate: Key chiral precursor in the research and development of new therapeutic agents, particularly in central nervous system (CNS) or anti-cancer drug candidates.
- Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
- Asymmetric Synthesis: Employed as a starting material or reagent in stereoselective synthesis due to its defined (S)-configuration, enabling the construction of complex chiral molecules.
- Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing related compounds or impurities.
- Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, dyes, or advanced materials requiring a specific tetrahydroquinoline framework.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 4H-Dibenzo(De,G)Quinolin-9-Ol, 5,6,6A,7-Tetrahydro-1,2,10-Trimethoxy-6 -Methyl-, (S)- |
| CAS No. | 2169-44-0 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | 341.40 g/mol |
| Synonyms | (S)-Bulbocapnine; (S)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-9-ol; (-)-Bulbocapnine; L-Bulbocapnine; Bulbocapnine (S-form); NSC 169864; BRN 0093972 |
| EINECS | Contact for details |
Quality Control
Every batch of our (S)-Bulbocapnine (CAS 2169-44-0) is produced and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure the identity, purity, and consistency required for research and development applications. A detailed Certificate of Analysis (COA) including chiral purity, assay, and impurity profile is supplied with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥97.0% |
| Chiral Purity (Chiral HPLC) | ≥98.0% (S)-enantiomer |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.5% |
| Heavy Metals | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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