Description

Tetrahydropyranyldiethyleneglycol CAS NO 2163-11-3 is a versatile chemical intermediate featuring a tetrahydropyranyl protecting group linked to a diethylene glycol chain. This compound matters for its utility in organic synthesis, particularly as a protecting group reagent for alcohols and in the preparation of specialty polymers and surfactants. It is needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing novel compounds and functional materials.

Application

• As a protecting group reagent for hydroxyl functions in multi-step organic synthesis, particularly in pharmaceutical intermediate manufacturing.
• Key intermediate in the synthesis of specialty surfactants and non-ionic detergents with unique solubility profiles.
• Building block for functional polymers and dendrimers used in drug delivery systems and coatings.
• Precursor in agrochemical research for creating novel active ingredients with enhanced properties.
• Used in the formulation of specialty solvents and plasticizers for high-performance applications.
• Intermediate for crown ether analogs and phase-transfer catalysts used in selective chemical reactions.

Basic Information

Product Name	Tetrahydropyranyldiethyleneglycol
CAS No.	2163-11-3
Molecular Formula	C9H18O4
Molecular Weight	190.24 g/mol
Synonyms	2-[2-(2-Tetrahydropyranyloxy)ethoxy]ethanol; Diethylene Glycol Monotetrahydropyranyl Ether; THP-DEG; 2-(2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy)ethanol; Tetrahydropyran-2-yl 2-(2-hydroxyethoxy)ethyl ether; Glycol Ether THP; THP Protected Diethylene Glycol; NSC 403697
EINECS	218-490-6

Quality Control

Our Tetrahydropyranyldiethyleneglycol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, identity confirmation, and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, physical properties, and chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.450 - 1.455
Density (g/mL at 20°C)	1.05 - 1.10

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.