Description

2-Bromo-3-Nitrothiophene is a versatile and high-purity brominated nitroheterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactivity, particularly in cross-coupling reactions and as a precursor for complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides.
• Material Science Research: Serves as a precursor for organic electronic materials, such as conductive polymers and organic semiconductors.
• Chemical Research & Development: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex thiophene derivatives.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and catalysts used in homogeneous catalysis.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and pigments.

Basic Information

Item	Details
Product Name	2-Bromo-3-Nitrothiophene
CAS No.	2161-96-8
Molecular Formula	C4H2BrNO2S
Molecular Weight	207.03 g/mol
Synonyms	3-Nitro-2-bromothiophene; 2-Bromo-3-nitrothiophene; Thiophene, 2-bromo-3-nitro-; 2-Bromothiophene-3-nitrile (incorrect but common misnomer); 2-Bromo-3-nitro-thiophene; Bromonitrothiophene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Nitrothiophene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Melting Point	~48-52 °C
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.