Description

Methyl 3,4-Dihydroxybenzoate is a high-purity synthetic phenolic ester, also known as Methyl Protocatechuate, with the CAS registry number 2150-43-8. This compound serves as a versatile and critical chemical intermediate and functional additive in advanced manufacturing processes. It is essential for industries requiring antioxidant properties, UV stabilization, or specific phenolic frameworks, including pharmaceuticals, cosmetics, and polymer science.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a protocatechuic acid backbone.
• Antioxidant Agent: Functions as a stabilizer in cosmetic formulations, personal care products, and certain food-grade applications to prevent oxidative degradation.
• Polymer Additive: Acts as a light stabilizer and antioxidant in specialty polymers and coatings to enhance durability and lifespan.
• Chemical Synthesis Building Block: A key starting material or intermediate for synthesizing more complex organic molecules, including flavors, fragrances, and agrochemicals.
• Research & Development: Employed in biochemical and pharmacological research as a reference standard or tool compound due to its bioactive properties.

Basic Information

Product Name	Methyl 3,4-Dihydroxybenzoate
CAS No.	2150-43-8
Molecular Formula	C8H8O4
Molecular Weight	168.15 g/mol
Synonyms	Methyl Protocatechuate; Protocatechuic Acid Methyl Ester; 3,4-Dihydroxybenzoic Acid Methyl Ester; Benzoic acid, 3,4-dihydroxy-, methyl ester; Methyl 3,4-dihydroxybenzoate; 4-Hydroxy-3-methoxybenzoic Acid Methyl Ester (common misnomer); Methyl Gallate Isomer
EINECS	218-437-1

Quality Control

Our Methyl 3,4-Dihydroxybenzoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC for assay and purity, and IR for identification, to ensure it meets precise specifications. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain optimal purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	138°C - 142°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.