Description

5-Bromo-4-Chloroquinazoline is a high-purity halogenated quinazoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its versatile reactivity, serving as a key precursor for constructing complex heterocyclic scaffolds with significant biological activity. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tyrosine kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	5-Bromo-4-Chloroquinazoline
CAS No.	2148-38-1
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	4-Chloro-5-bromoquinazoline; Quinazoline, 5-bromo-4-chloro-; 5-Bromo-4-chloro-quinazoline; 2148-38-1; 4-Chloro-5-bromo-quinazoline; 5-Bromo-4-chloroquinazoline; 5-Brom-4-chlor-chinazolin (German); 5-ブロモ-4-クロロキナゾリン (Japanese)
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloroquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.