Description

2,2'-Dithiodipyridine is a versatile organosulfur compound featuring a disulfide bridge between two pyridine rings. This structure makes it a valuable reagent for biochemical research, particularly in protein chemistry and as a thiol-specific crosslinking or modifying agent. It is essential for laboratories and manufacturers in the pharmaceutical, biotechnology, and life science sectors requiring high-purity intermediates for synthesis and analysis.

Application

• Protein Biochemistry & Thiol Modification: Used as a specific reagent for the modification of cysteine residues in proteins and peptides.
• Crosslinking Agent: Serves as a homobifunctional crosslinker for introducing disulfide bonds between biomolecules.
• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents.
• Bioconjugation: Facilitates the conjugation of drugs, labels, or probes to thiol-containing molecules.
• Analytical Chemistry: Employed as a derivatization agent in HPLC and other analytical methods for thiol detection.
• Polymer Science: Acts as a chain transfer agent or modifier in the synthesis of functional polymers.

Basic Information

Product Name	2,2'-Dithiodipyridine
CAS No.	2127-03-9
Molecular Formula	C10H8N2S2
Molecular Weight	220.31 g/mol
Synonyms	2,2'-Dipyridyl disulfide; 2,2'-Dithiobispyridine; 2,2'-Dithiodipyridine; Aldrithiol™-2; 2-Pyridyl disulfide; DTDP; Bis(2-pyridyl) disulfide; 2,2'-Dithiopyridine; 2,2'-Pyridyl disulfide
EINECS	218-327-8

Quality Control

Our 2,2'-Dithiodipyridine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	56 - 60 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.