Description

1,3-Difluoro-2,4-Dinitrobenzene, 98% is a high-purity aromatic compound featuring a benzene ring substituted with two fluorine atoms and two nitro groups in specific positions. This molecular structure makes it a valuable and versatile building block for advanced organic synthesis, particularly in the development of complex molecules. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides, where the difluoro-dinitro moiety can contribute to biological activity and selectivity.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex, high-performance dyes and pigments due to its electron-withdrawing nitro groups.
• Cross-coupling Reactions: A valuable substrate for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to create more complex biaryl structures.
• Nucleophilic Aromatic Substitution: The fluorine atoms are excellent leaving groups, making this compound highly reactive in SNAr reactions for introducing various nucleophiles.

Basic Information

Product Name	1,3-Difluoro-2,4-Dinitrobenzene, 98%
CAS No.	2106-41-4
Molecular Formula	C6H2F2N2O4
Molecular Weight	204.09 g/mol
Synonyms	2,4-Dinitro-1,3-difluorobenzene; 1,3-Difluoro-2,4-dinitrobenzene; Benzene, 1,3-difluoro-2,4-dinitro-; 2,4-Dinitro-meta-difluorobenzene; m-Difluoro-2,4-dinitrobenzene; NSC 404083; 1,3-Difluoro-2,4-dinitrobenzol
EINECS	218-276-5

Quality Control

Our 1,3-Difluoro-2,4-Dinitrobenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure the specified purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with our rigorous specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	93 - 97 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.