Description

2-Chloromethyl-Benzo[B]Thiophene is a versatile and high-value heterocyclic building block, specifically a chloromethylated benzothiophene derivative. This compound is critical for the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold's bioactivity.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloromethyl-Benzo[B]Thiophene
CAS No.	2076-88-2
Molecular Formula	C9H7ClS
Molecular Weight	182.67 g/mol
Synonyms	2-(Chloromethyl)benzo[b]thiophene; 2-(Chloromethyl)-1-benzothiophene; 1-Benzothiophene, 2-(chloromethyl)-; Benzo[b]thiophene, 2-(chloromethyl)-; 2-Chloromethyl-1-benzothiophene; 2-Chloromethylbenzothiophene; 2-Chloromethylbenzo[b]thiophene
EINECS	218-194-5

Quality Control

Every batch of 2-Chloromethyl-Benzo[B]Thiophene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.