Description

2-Bromo-2'-Nitro-4'-(Trifluoromethyl)Diphenyl Ether is a specialized halogenated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring bromine, nitro, and trifluoromethyl substituents, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and pesticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Electronics: Investigated as a building block for electron-transport materials or non-linear optical (NLO) chromophores in OLEDs and other devices.
• Chemical Biology Probes: Utilized to create labeled compounds or affinity probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination to create complex biaryl systems.

Basic Information

Product Name	2-Bromo-2'-Nitro-4'-(Trifluoromethyl)Diphenyl Ether
CAS No.	2069-14-9
Molecular Formula	C₁₃H₇BrF₃NO₃
Molecular Weight	362.10 g/mol
Synonyms	1-Bromo-2-(2-nitro-4-(trifluoromethyl)phenoxy)benzene; 2-Bromo-1-(2-nitro-4-(trifluoromethyl)phenoxy)benzene; 2-Bromo-2'-nitro-4'-(trifluoromethyl)diphenyl ether; 2'-Nitro-4'-(trifluoromethyl)-2-bromodiphenyl ether; [1,1'-Biphenyl]-2-bromo-2'-nitro-4'-(trifluoromethyl) ether; Ether, 2-bromo-2'-nitro-4'-(trifluoromethyl)diphenyl
EINECS	Contact for details

Quality Control

Our 2-Bromo-2'-Nitro-4'-(Trifluoromethyl)Diphenyl Ether is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.