Description

1-Benzothiophene-5-Carboxylic Acid is a high-purity organic building block and key heterocyclic intermediate of significant commercial and research interest. Its value lies in its functionalized benzothiophene core, which serves as a versatile scaffold for synthesizing more complex molecules. This compound is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for applications in drug discovery, crop protection, and organic electronics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzothiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich aromatic system.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized dyes and fluorescent markers.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	1-Benzothiophene-5-Carboxylic Acid
CAS No.	2060-64-2
Molecular Formula	C9H6O2S
Molecular Weight	178.21 g/mol
Synonyms	Benzothiophene-5-carboxylic Acid; 5-Carboxybenzothiophene; 1-Benzothiophene-5-carboxylic acid; 5-Benzothiophenecarboxylic Acid; Thianaphthene-5-carboxylic Acid; NSC 403697; 5-Benzothienylcarboxylic Acid; Benzo[b]thiophene-5-carboxylic acid
EINECS	218-158-1

Quality Control

Our 1-Benzothiophene-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.