Description

4-(2-Hydroxyethyl)-4-Methyl-1,3-Dioxane is a versatile cyclic acetal and diol derivative with significant utility as a specialty chemical intermediate. Its unique bifunctional structure, featuring both a protected diol moiety and a reactive hydroxyl group, makes it a valuable building block for controlled synthesis. This compound is primarily sought by R&D chemists and process engineers in the fine chemical and pharmaceutical sectors for developing novel polymers, stabilizers, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug molecules, particularly where controlled release or specific stereochemistry is required.
• Polymer & Resin Modifier: Used to introduce hydroxyl functionality and acetal linkages into polymer backbones, enhancing properties like flexibility, adhesion, and chemical resistance.
• Crosslinking Agent: Functions in thermosetting resin systems, such as certain epoxy or polyurethane formulations, to improve network density and thermal stability.
• Solvent & Co-solvent: Acts as a high-boiling, polar aprotic solvent in specialized organic reactions and coating applications.
• Stabilizer Precursor: Utilized in the production of additives for plastics, fuels, and lubricants to prevent degradation from heat, light, or oxidation.
• Fragrance & Flavor Chemistry: Employed as an intermediate for creating specific acetal-based aroma chemicals with fruity or green notes.

Basic Information

Product Name	4-(2-Hydroxyethyl)-4-Methyl-1,3-Dioxane
CAS No.	2018-45-3
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	4-Methyl-4-(2-hydroxyethyl)-1,3-dioxane; 2-(4-Methyl-1,3-dioxan-4-yl)ethanol; 4-(2-Hydroxyethyl)-4-methyl-m-dioxane; 1,3-Dioxane, 4-(2-hydroxyethyl)-4-methyl-; Ethanol, 2-(4-methyl-1,3-dioxan-4-yl)-
EINECS	217-955-8

Quality Control

Our production of 4-(2-Hydroxyethyl)-4-Methyl-1,3-Dioxane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed against comprehensive specifications using advanced techniques like GC, HPLC, and NMR. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.455
Density (g/mL at 20°C)	1.070 - 1.090

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.