Description

4-Ethoxy-2,3,5,6-tetrafluorobenzotrifluoride is a high-value fluorinated aromatic building block, distinguished by its unique combination of ethoxy and multiple fluorine substituents. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures, enabling the development of materials with enhanced performance characteristics. It is primarily sought after by R&D and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise chemical modification.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic motifs that can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides where the fluorinated core contributes to product efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of fluorinated components for electronic display materials, leveraging its electronic properties to tune performance.
• Polymer & Resin Modification: Employed to incorporate fluorine into polymer backbones or side chains, enhancing chemical resistance, thermal stability, and surface properties of high-performance plastics and coatings.
• Organic Synthesis & Catalysis Research: A valuable reagent in academic and industrial research for exploring new fluorination methodologies and constructing complex, fluorinated organic molecules.

Basic Information

Product Name	4-Ethoxy-2,3,5,6-Tetrafluorobenzotrifluoride
CAS No.	2002-99-5
Molecular Formula	C9H5F7O
Molecular Weight	262.12 g/mol
Synonyms	1-Ethoxy-2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene; 2,3,5,6-Tetrafluoro-4-ethoxybenzotrifluoride; 4-Ethoxy-2,3,5,6-tetrafluoro-α,α,α-trifluorotoluene; Pentafluoro(ethoxy)benzotrifluoride; Benzene, 1-ethoxy-2,3,5,6-tetrafluoro-4-(trifluoromethyl)-; Ethoxy-pentafluorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our production of 4-Ethoxy-2,3,5,6-tetrafluorobenzotrifluoride adheres to stringent internal quality standards to ensure batch-to-batch consistency and purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.