Description

1,4,7,10,13,16,19,22-Octaaza-Cyclotetracosane is a sophisticated macrocyclic polyamine ligand, also known as a cyclen derivative, with the CAS registry number 297-11-0. This compound is highly valued for its strong and selective chelating properties, enabling the formation of stable complexes with a wide range of metal ions. It serves as a critical building block and precursor in advanced research and industrial applications, particularly in the fields of medicinal chemistry, catalysis, and materials science. Professionals in pharmaceuticals, chemical synthesis, and diagnostic imaging rely on its consistent quality and performance.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of MRI contrast agents (Gadolinium-based) and radiopharmaceuticals.
• Catalysis & Ligand Chemistry: Acts as a versatile ligand for transition metal catalysts used in organic synthesis and polymerization reactions.
• Chemical Sensing & Analysis: Employed in the development of fluorescent sensors and selective ionophores for analytical chemistry.
• Materials Science: Used in the creation of functionalized surfaces, metal-organic frameworks (MOFs), and advanced polymeric materials.
• Bioconjugation & Labeling: Facilitates the attachment of metal chelates to biomolecules (antibodies, peptides) for diagnostic and therapeutic purposes.
• Wastewater Treatment: Potential application in heavy metal ion sequestration and recovery processes.

Basic Information

Product Name	1,4,7,10,13,16,19,22-Octaaza-Cyclotetracosane
CAS No.	297-11-0
Molecular Formula	C16H40N8
Molecular Weight	344.54 g/mol
Synonyms	1,4,7,10,13,16,19,22-Octaazacyclotetracosane; Cyclen; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid precursor; Tetrakis(2-aminoethyl)ethylenediamine cyclic tetramer; TAEC; [12]aneN4 (derivative); 1,4,7,10-Tetraazacyclododecane, 1,4,7,10-tetrakis(2-aminoethyl)-; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraethanamine
EINECS	206-048-1

Quality Control

Our 1,4,7,10,13,16,19,22-Octaaza-Cyclotetracosane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at room temperature (15-25°C/59-77°F). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.