Description

8-Azabicyclo[5.1.0]octane is a strained bicyclic organic compound featuring a three-membered aziridine ring fused to a seven-membered ring, making it a valuable and versatile synthetic intermediate. Its unique bridged structure and nitrogen-containing heterocycle are crucial for constructing complex molecular architectures in advanced chemical synthesis. This building block is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and for creating complex nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require strained-ring systems for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific chemical properties.
• Academic and R&D Laboratories: A fundamental building block for methodological studies in organic chemistry, including ring-opening and strain-release reactions.

Basic Information

Product Name	8-Azabicyclo[5.1.0]octane
CAS No.	286-44-2
Molecular Formula	C7H13N
Molecular Weight	111.18 g/mol
Synonyms	8-Azabicyclo[5.1.0]octane; 1-Azaspiro[2.6]nonane; Octahydro-1H-cyclopropa[b]azepine; Bicyclo[5.1.0]octane, 8-aza-; 8-Azabicyclo[5.1.0]octane; 286-44-2
EINECS	Contact for details

Quality Control

Every batch of 8-Azabicyclo[5.1.0]octane is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.