Description

Naphthalene 1,2-Oxide CAS NO 277-50-9 is a reactive epoxide derivative of naphthalene, serving as a crucial synthetic intermediate in advanced organic chemistry. Its strained three-membered oxirane ring makes it a valuable electrophile for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This high-purity building block is essential for research chemists and process development scientists working in fine chemical synthesis, material science, and metabolic studies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug metabolites for pharmacological studies.
• Agrochemical Research: Used in developing novel pesticides, herbicides, and plant growth regulators through targeted ring-opening reactions.
• Fine Chemical Synthesis: Serves as a versatile electrophile for creating specialty chemicals, dyes, and functional materials.
• Polymer Science: Employed in the research and development of epoxy resins and other polymeric materials with specific thermal or mechanical properties.
• Metabolic Pathway Studies: Utilized as a model compound in biochemical and toxicological research to study epoxide hydrolase activity and metabolic activation pathways.
• Academic & Industrial R&D: Fundamental building block in organic chemistry laboratories for method development and exploring new synthetic routes.

Basic Information

Product Name	Naphthalene 1,2-Oxide
CAS No.	277-50-9
Molecular Formula	C₁₀H₈O
Molecular Weight	144.17 g/mol
Synonyms	1,2-Epoxynaphthalene; Naphthalene Epoxide; 1,2-Naphthylene Oxide; 1,2-Dihydronaphtho[1,2-b]oxirene; Naphthalene Oxide; 1,2-Naphthalene Oxide; Naphtho[1,2-b]oxirene; 1,2-Epoxy-1,2-dihydronaphthalene
EINECS	205-987-9

Quality Control

Our Naphthalene 1,2-Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere to minimize potential decomposition. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.