Description

tert-Butyl 3-Hydrazinylazetidine-1-Carboxylate Hydrochloride is a high-purity, protected azetidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex nitrogen-containing heterocycles, which are central to modern drug discovery programs. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of azetidine-based drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the azetidine scaffold.
• Peptidomimetics Development: Employed in the design and synthesis of conformationally constrained peptide analogs.
• Agrochemical Synthesis: Serves as a precursor for novel crop protection agents and herbicides.
• Chemical Biology Probes: Useful for creating tool compounds to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules at various scales.

Basic Information

Product Name	tert-Butyl 3-Hydrazinylazetidine-1-Carboxylate Hydrochloride
CAS No.	1998216-27-5
Molecular Formula	C8H18ClN3O2
Molecular Weight	223.70 g/mol
Synonyms	1-Boc-3-hydrazinylazetidine hydrochloride; tert-Butyl 3-hydrazinyl-1-azetidinecarboxylate hydrochloride; 3-Hydrazinylazetidine-1-carboxylic acid tert-butyl ester hydrochloride; 1-(tert-Butoxycarbonyl)-3-hydrazinylazetidine hydrochloride; Azetidine-3-hydrazine, 1-Boc-protected, hydrochloride; Boc-3-hydrazinoazetidine HCl; 1998216-27-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Hydrazinylazetidine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.