Description

2-Amino-2-(5-Fluoro-2-Hydroxyphenyl)Acetic Acid Hydrochloride is a high-purity, fluorinated aromatic amino acid derivative with significant synthetic utility. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is essential for research and production in pharmaceutical chemistry, agrochemical development, and advanced material science, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and pesticides that leverage its fluorinated phenolic structure.
• Peptide Mimetics & Conjugation: Serves as a non-natural amino acid analog for constructing peptide-based drugs and bioconjugates with enhanced metabolic stability.
• Ligand & Catalyst Development: Employed in organometallic chemistry for creating novel chiral ligands and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design of molecular probes and fluorescent tags for studying biological processes and enzyme mechanisms.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	2-Amino-2-(5-Fluoro-2-Hydroxyphenyl)Acetic Acid Hydrochloride
CAS No.	1998215-80-7
Molecular Formula	C8H9FNO3·HCl
Molecular Weight	237.62 g/mol (Free base: 199.16 g/mol)
Synonyms	(5-Fluoro-2-hydroxyphenyl)glycine hydrochloride; 2-Amino-2-(5-fluoro-2-hydroxyphenyl)ethanoic acid hydrochloride; 5-Fluoro-2-hydroxy-DL-phenylglycine hydrochloride; α-Amino-(5-fluoro-2-hydroxyphenyl)acetic acid hydrochloride; 2-(5-Fluoro-2-hydroxyphenyl)glycine HCl; FHPG hydrochloride; DL-5-Fluoro-2-hydroxyphenylglycine hydrochloride; (5-Fluoro-2-hydroxybenzyl)aminoacetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to support our commitment to reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.