Description

1,3-Dioxane, 5-Butyl-2-(3,5-Difluorophenyl)-, trans- is a specialized fluorinated dioxane derivative with the CAS number 1983995-73-8. This compound serves as a valuable high-purity building block and key intermediate in advanced organic synthesis, particularly where its unique stereochemistry and fluorine substitution are critical. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used as a precursor in the creation of advanced herbicides and fungicides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a core structure or intermediate in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in asymmetric synthesis and fluorine chemistry.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific, high-value fluorinated heterocycles.

Basic Information

Product Name	1,3-Dioxane, 5-Butyl-2-(3,5-Difluorophenyl)-, trans-
CAS No.	1983995-73-8
Molecular Formula	C14H18F2O2
Molecular Weight	256.29 g/mol
Synonyms	trans-5-Butyl-2-(3,5-difluorophenyl)-1,3-dioxane; (trans)-5-Butyl-2-(3,5-difluorophenyl)-1,3-dioxane; 5-Butyl-2-(3,5-difluorophenyl)-1,3-dioxane, trans-; 2-(3,5-Difluorophenyl)-5-butyl-1,3-dioxane; 1,3-Dioxane, 5-butyl-2-(3,5-difluorophenyl)-, (2R,5R)-rel-; Butyl-difluorophenyl-dioxane; BDFD; Fluorinated dioxane derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxane, 5-Butyl-2-(3,5-Difluorophenyl)-, trans- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.