Description

Ethyl 6-Azaspiro[2.5]octane-1-carboxylate hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries to synthesize new drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry: Serves as a starting material or intermediate in the development of scalable API synthesis routes.
• Chemical Biology: Employed in the design and synthesis of molecular probes for biological target identification and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-phase drug development.
• Academic Research: Utilized in university and institutional labs for the exploration of new heterocyclic chemistry and bioactivity.

Basic Information

Product Name	Ethyl 6-Azaspiro[2.5]octane-1-carboxylate hydrochloride
CAS No.	1983157-41-0
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	Ethyl 6-azaspiro[2.5]octane-1-carboxylate HCl; 1-Carbethoxy-6-azaspiro[2.5]octane hydrochloride; 6-Azaspiro[2.5]octane-1-carboxylic acid ethyl ester hydrochloride; Ethyl 1-azaspiro[2.5]octane-6-carboxylate hydrochloride (alternative numbering); Azaspirooctane carboxylate ester hydrochloride; CAS 1983157-41-0
EINECS	Contact for details

Quality Control

Our Ethyl 6-Azaspiro[2.5]octane-1-carboxylate hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and current industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.