Description

(4-Bromo-2,3-Difluorophenyl)Methanamine Hydrochloride is a high-purity, halogenated benzylamine hydrochloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic amine scaffold essential for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl and bromo substituents.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers and liquid crystals where the introduction of fluorine and bromine atoms modifies physical properties.
• Chemical Biology Probes: Utilized to create tagged molecules or affinity probes for studying biological pathways and protein interactions.

Basic Information

Product Name	(4-Bromo-2,3-Difluorophenyl)Methanamine Hydrochloride
CAS No.	1980086-47-2
Molecular Formula	C7H7BrClF2N
Molecular Weight	258.49 g/mol
Synonyms	1-(4-Bromo-2,3-difluorophenyl)methanamine hydrochloride; (4-Bromo-2,3-difluorobenzyl)amine hydrochloride; 4-Bromo-2,3-difluorobenzylamine hydrochloride; α-Amino-4-bromo-2,3-difluorotoluene hydrochloride; 2,3-Difluoro-4-bromobenzylamine HCl; 4-Bromo-2,3-difluoro-benzenemethanamine hydrochloride; Benzenemethanamine, 4-bromo-2,3-difluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our (4-Bromo-2,3-Difluorophenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and ensure compliance with relevant global regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.