Description

8-Oxa-5-Azaspiro[3.5]Nonane Oxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing complex drug candidates, especially those targeting neurological disorders.
• Organic Synthesis Reagent: Used in research laboratories for constructing spirocyclic and heterocyclic frameworks in medicinal chemistry.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Preclinical & Clinical Research: Employed in the development and scale-up of new chemical entities (NCEs) during drug discovery pipelines.
• Process Chemistry: Integral to route scouting and optimization for the efficient, scalable production of target molecules.
• Academic Research: Used in university and institutional labs for studying novel synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	8-Oxa-5-Azaspiro[3.5]Nonane Oxalate
CAS No.	1980053-02-8
Molecular Formula	C9H13NO5
Molecular Weight	215.20 g/mol
Synonyms	8-Oxa-5-azaspiro[3.5]nonane oxalate; 5-Azaspiro[3.5]nonan-8-one oxime oxalate (related); Oxaspiro nonane oxalate; Spirocyclic oxazolidinone precursor; 1-Oxa-4-azaspiro[4.4]nonane oxalate (isomer); CAS 1980053-02-8; 8-Oxa-5-azaspiro[3.5]nonane, oxalic acid salt
EINECS	Contact for details

Quality Control

Our 8-Oxa-5-Azaspiro[3.5]Nonane Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.