Description

5-Bromo-2-Iodo-[1,2,4]Triazolo[1,5-A]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require sophisticated intermediates for drug discovery and functional material creation.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the triazolopyridine scaffold for bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for OLEDs (Organic Light-Emitting Diodes) and other optoelectronic devices.
• Chemical Biology & Probe Development: Utilized in the design of molecular probes and tags for studying biological processes and enzyme mechanisms due to its halogen handles for further functionalization.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) to create diverse compound libraries.
• Ligand Synthesis: Employed in the preparation of novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	5-Bromo-2-Iodo-[1,2,4]Triazolo[1,5-A]Pyridine
CAS No.	1980050-20-1
Molecular Formula	C6H2BrIN3
Molecular Weight	338.91 g/mol
Synonyms	5-Bromo-2-iodo-[1,2,4]triazolo[1,5-a]pyridine; 2-Iodo-5-bromo-[1,2,4]triazolo[1,5-a]pyridine; [1,2,4]Triazolo[1,5-a]pyridine, 5-bromo-2-iodo-; 5-Bromo-2-iodo-1,2,4-triazolo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-[1,2,4]Triazolo[1,5-A]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C), and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.