Description

(S)-1-(3-Fluoro-4-Methoxyphenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for the synthesis of advanced pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its defined stereochemistry and functionalized aromatic ring make it a critical component for medicinal chemists developing targeted therapies. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drugs, particularly in areas requiring specific enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of new chemical entities (NCEs) and proprietary drugs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block in multi-step synthetic routes for complex target molecules.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to introduce the (S)-configured amine center.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry & Scale-Up: Suitable for development from laboratory-scale research to pilot plant and commercial manufacturing.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(S)-1-(3-Fluoro-4-Methoxyphenyl)Ethanamine Hydrochloride
CAS No.	1980007-86-0
Molecular Formula	C9H13ClFNO
Molecular Weight	205.66 g/mol
Synonyms	(S)-1-(3-Fluoro-4-methoxyphenyl)ethan-1-amine hydrochloride; (S)-α-Methyl-3-fluoro-4-methoxybenzylamine hydrochloride; (S)-1-(3-Fluoro-4-methoxyphenyl)ethylamine HCl; (S)-3-Fluoro-4-methoxy-α-methylbenzylamine hydrochloride; (S)-FMEA HCl; (1S)-1-(3-Fluoro-4-methoxyphenyl)ethanaminium chloride
EINECS	Contact for details

Quality Control

Our (S)-1-(3-Fluoro-4-Methoxyphenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.