Description

(R)-(Pyrrolidin-3-Yloxy)-Acetic Acid Methyl Ester Tosylate is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its core value lies in providing a versatile, enantiomerically pure building block for the construction of complex molecules, particularly those with a pyrrolidine scaffold. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used in the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in stereoselective transformations.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and methodological studies in universities and contract research organizations (CROs).
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and conformationally restricted bioactive molecules.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value, specialized chemicals.

Basic Information

Product Name	(R)-(Pyrrolidin-3-Yloxy)-Acetic Acid Methyl Ester Tosylate
CAS No.	1965314-51-5
Molecular Formula	C15H23NO6S
Molecular Weight	345.41 g/mol
Synonyms	Methyl (R)-2-((pyrrolidin-3-yl)oxy)acetate 4-methylbenzenesulfonate; (R)-Methyl 2-((pyrrolidin-3-yl)oxy)acetate tosylate; (R)-3-[(Methoxycarbonyl)methoxy]pyrrolidine p-toluenesulfonate; (R)-Pyrrolidin-3-yloxy-acetic acid methyl ester tosylate; (R)-Methyl (3-pyrrolidinyloxy)acetate tosylate salt; (R)-Methyl 2-(3-pyrrolidinyloxy)acetate 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our (R)-(Pyrrolidin-3-Yloxy)-Acetic Acid Methyl Ester Tosylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.