Description

6-Bromo-7-Fluoro-1,2,3,4-Tetrahydro-Quinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1965309-30-1. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), offering a versatile halogenated scaffold for structure-activity relationship (SAR) studies. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used for lead optimization and SAR studies due to its halogenated quinoline core, which is a privileged structure in drug discovery.
• Agrochemical Development: Serves as a precursor in the research and development of new pesticides and herbicides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for organic synthesis methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	6-Bromo-7-Fluoro-1,2,3,4-Tetrahydro-Quinoline Hydrochloride
CAS No.	1965309-30-1
Molecular Formula	C9H8BrClFN
Molecular Weight	264.52 g/mol
Synonyms	6-Bromo-7-fluoro-1,2,3,4-tetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydro-6-bromo-7-fluoroquinoline hydrochloride; 6-Bromo-7-fluoro-1,2,3,4-tetrahydroquinoline HCl; 6-Bromo-7-fluoro-3,4-dihydro-2H-quinoline hydrochloride; 1965309-30-1; Quinoline, 6-bromo-7-fluoro-1,2,3,4-tetrahydro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Fluoro-1,2,3,4-Tetrahydro-Quinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP development and pre-clinical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.