Description

2-Iodo-1-Methanesulfonyl-4-Methoxy-Benzene is a specialized organosulfur and organoiodine compound that serves as a valuable building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing mesyl group and an iodine atom on an aromatic ring, makes it a versatile intermediate for constructing complex molecules. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the iodine atom for further functionalization.
• Material Science: Serves as a building block for creating specialized organic electronic materials and liquid crystals.
• Chemical Synthesis: Employed in academic and industrial R&D labs as a reagent for introducing the methanesulfonyl (mesyl) and iodo functional groups into complex molecular architectures.
• Ligand and Catalyst Development: Useful in the preparation of novel ligands for metal catalysis due to its modifiable aromatic system.

Basic Information

Product Name	2-Iodo-1-Methanesulfonyl-4-Methoxy-Benzene
CAS No.	1965309-05-0
Molecular Formula	C8H9IO3S
Molecular Weight	312.12 g/mol
Synonyms	1-Methoxy-2-iodo-4-(methanesulfonyl)benzene; 4-Methoxy-2-iodophenyl methyl sulfone; 2-Iodo-4-methoxyphenyl methyl sulfone; 1-Iodo-2-methanesulfonyl-4-methoxybenzene; Methyl (2-iodo-4-methoxyphenyl) sulfone; Mesityl 2-iodo-4-methoxy sulfone (common name); 2-Iodo-4-methoxybenzenesulfonyl methane
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for all our fine chemical intermediates. Each batch of 2-Iodo-1-Methanesulfonyl-4-Methoxy-Benzene is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.