Description

(R)-1,2,3,4-Tetrahydro-Quinolin-4-Ylamine Hydrochloride is a high-purity chiral amine building block essential for modern pharmaceutical and fine chemical synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), enabling the creation of molecules with specific stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a versatile building block in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for use in stereoselective transformations.
• Academic & Process Chemistry: A valuable reagent for method development and scaling chiral synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	(R)-1,2,3,4-Tetrahydro-Quinolin-4-Ylamine Hydrochloride
CAS No.	1965305-32-1
Molecular Formula	C9H13ClN2
Molecular Weight	184.67 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydroquinolin-4-amine hydrochloride; (4R)-1,2,3,4-Tetrahydroquinolin-4-amine hydrochloride; (R)-4-Amino-1,2,3,4-tetrahydroquinoline hydrochloride; (R)-THQA HCl; (R)-Tetrahydoquinolin-4-ylamine HCl; (R)-4-Aminotetrahydroquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1,2,3,4-Tetrahydro-Quinolin-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.