Description

2,6-Diaza-Spiro[3.4]Octan-7-One Toluene-4-Sulfonic Acid Salt is a high-purity, advanced pharmaceutical intermediate featuring a constrained spirocyclic scaffold. This compound is of significant value in modern drug discovery for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in developing small molecule drugs targeting central nervous system disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique spirocyclic diaza structure, which can improve metabolic stability and binding affinity.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional PROTAC molecules for targeted protein degradation.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Employed in route scouting and process development for the commercial-scale manufacturing of candidate drugs.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the global biopharma industry.

Basic Information

Product Name	2,6-Diaza-Spiro[3.4]Octan-7-One Toluene-4-Sulfonic Acid Salt
CAS No.	1958100-97-4
Molecular Formula	C13H18N2O4S
Molecular Weight	298.36 g/mol
Synonyms	2,6-Diazaspiro[3.4]octan-7-one 4-methylbenzenesulfonate; 7-Oxo-2,6-diazaspiro[3.4]octane p-toluenesulfonate salt; 2,6-Diaza-spiro[3.4]octane-7-one tosylate salt; Tosic acid salt of 2,6-diazaspiro[3.4]octan-7-one; 1958100-97-4; Spirocyclic diazaoctanone tosylate; 2,6-Diaza-Spiro[3.4]Octan-7-One TsOH Salt
EINECS	Contact for details

Quality Control

Our 2,6-Diaza-Spiro[3.4]Octan-7-One Toluene-4-Sulfonic Acid Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.